Prenatal and postnatal growth failure associated with maternal heterodisomy for chromosome 7.
نویسندگان
چکیده
منابع مشابه
Prenatal and postnatal growth failure associated with maternal heterodisomy for chromosome 7.
The association of maternal uniparental disomy for chromosome 7 and postnatal growth failure has been reported in four cases and suggests the presence of genomic imprinting of one or more growth related genes on chromosome 7. However, in the reported cases, the possibility of homozygosity for a recessive mutation could not be excluded as the cause of the growth failure as in all cases isodisomy...
متن کاملCharacterization of an autism-associated segmental maternal heterodisomy of the chromosome 15q11-13 region.
Cytogenetic abnormalities in the Prader-Willi/Angelman syndrome (PWS/AS) critical region have been described in individuals with autism. Maternal duplications and linkage disequilibrium in families with autism suggest the existence of a susceptibility locus at 15q11-q13. Here, we describe a 6-year-old girl diagnosed with autism, developmental delay, and delayed expressive and receptive language...
متن کاملCoadaptation of prenatal and postnatal maternal effects.
In a wide variety of species, a female's age of first reproduction influences offspring size and survival, suggesting that there exists an optimal timing of reproduction. Mothers in many species also influence offspring size and survival after birth through variation in parental care. We experimentally separated these effects in the burying beetle Nicrophorus vespilloides to test for coadaptati...
متن کاملDisentangling prenatal and postnatal maternal genetic effects reveals persistent prenatal effects on offspring growth in mice.
Mothers are often the most important determinant of traits expressed by their offspring. These "maternal effects" (MEs) are especially crucial in early development, but can also persist into adulthood. They have been shown to play a role in a diversity of evolutionary and ecological processes, especially when genetically based. Although the importance of MEs is becoming widely appreciated, we k...
متن کاملThe Risks Associated With Maternal Antidepressant Use During the Prenatal and Postnatal Stages of Development
Over the past decade, maternal antidepressant use has skyrocketed in the United States. Maternal depression, which was once categorized as an extremely rare condition, is now the leading cause of disability in American women aged 18 to 44 (Stewart, 2005). In spite of the published data that document the risks associated with antidepressant use in maternal and pediatric populations, physicians t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1995
ISSN: 1468-6244
DOI: 10.1136/jmg.32.11.871